This image is part of a study in which a droplet of a liquid suspension of nanoparticles (PMMA, 190 nanometers in diameter) was placed onto a silicon surface and dried. This created a circular pattern sharing different particle densities. Nanoparticles are among the most controversial materials in science today. They could revolutionize drug delivery and enhance medical imaging, but they also provoke concerns about unknown influences to health and the environment. The imaging technique combines optical microscopy and scanning probe techniques—atomic force microscopes—that bridge the micro- and nanoscales.